① Pharmaceutical process development services
◆ strictly comply with the customer's requirements on the project time node and work quality
◆ strictly follow the guiding principles of SFDA drug process development
◆ provide "one-stop" process R & D and development services:
◆ route design, process development, process optimization, amplification and handover, impurity research, quality standard research, and assistance in registration and Application
◆ customized synthesis: synthesis of reference compounds from mg to kg
◆ compounds for structure-activity relationship study
◆ Reference compounds
◆ special chemical synthesis, such as asymmetric synthesis and chemical separation
② Custom synthesis service
◆ provide diversified and flexible customized services according to customer requirements
▶ Compound customization with complex structure
▶ Drug impurity identification and custom synthesis
◆ fully meet the customer's requirements for sample delivery time and quality
◆ cooperate with customers to confirm the structure of relevant certification (CMA)
◆ provide structural confirmation report meeting customer requirements
③ Pharmaceutical Chemistry
◆ synthesis and confirmation of HTS active compounds
◆ mother core design and improvement
◆ lead compound optimization
◆ achieve the toxicity and safety pharmacological data indicators of the drug to rodents through structural modification
◆ search for clinical candidate drugs with the most ideal physicochemical properties and drug properties through structural modification
◆ research on synthesis process chemistry / amplification preparation
◆ patent application
◆ customized cooperation scheme according to customer requirements
④ Solutions to specific problems
◆ solutions for specific process steps: actively communicate and solve the reaction defects that are difficult to solve in the process.
◆ API quality problem solution: improve the quality of intermediates or API through technological means.
◆ cost problem solution: reduce reaction steps, reduce intermediate or API production costs, and improve product competitiveness.
◆ patent circumvention solution: form new innovation points at the lowest cost to ensure the rationality of the production process
